Cyclophosphamide 500mg

What Is Cyclophosphamide 500mg? 

Cyclophosphamide 500mg helps to treat Nephrotic Syndrome and cancer cells. 

Cyclophosphamide is a Cytotoxic Drug widely used for treating malignant diseases in children and adults. 

It is the single agent that produces the objective remission of malignant conditions. 

The cyclophosphamide is used with a combination of various cytotoxic drugs, surgery, radiotherapy, and many more. 

Normally, all cyclophosphamide vials contain Cyclophosphamide Monohydrate, which is equivalent to 500 mg anhydrous cyclophosphamide. These can be especially reconstituted for varied intravenous use. 

The endoxan involves with Cyclophosphamide and it is indicated for the malignant diseases like the malignant lymphomas, Hodgkin’s disease, Burkitt’s lymphoma, Ewing’s sarcoma, breast cancer and more. 

The Role of Sanford Pharmacy:

Sanford Pharmacy recognizes the critical role that Cyclophosphamide plays in patient care. Visit the Sanford Pharmacy website and Order your Cyclophosphamide 500mg medicine today.

How Does Cyclophosphamide 500mg Work? 

Cyclophosphamide is an anti-cancer medication with an Alkylating Agent.

 The medicine works with extensively damaging genetic materials such as DNA and RNA in the cancer cells. 

These automatically stop the multiplication and growth of the cells, even within a short time.

 The endoxan 50 mg reduces the cancer cells in the body by preventing the growth and multiplication. 

Cyclophosphamide is also demonstrated with the cytostatic effect on varied tumours. 

The active metabolites involved in cyclophosphamide will be Alkylating Agents which transfer the Alkyl Groups to the DNA throughout the process. 

These activities would be extensively preventing the normal synthesis of DNA. 

Cyclophosphamide is also extensively well absorbed in the body with oral dosage. These involve oral and parenteral administration. Cyclophosphamide 500mg: Get it from our Reputed Online Sanford Pharmacy.

The cyclophosphamide dose is the inactive prodrug with alkylating metabolites produced by hepatic metabolism. These would be extensively reaching greater peak levels for about 4 to 6 hours. 

Hepatic enzymes could normally be included. Various compounds are also enabled with plasma protein, along with active metabolites, which are protein-bound to some extent.

 Cyclophosphamide 500mg is widely distributed in the blood-brain barrier, so the placental barrier acts as the ascites. 

These metabolites will be excreted really quickly, even without any hassle.

Cyclophosphamide belongs to a group of medicines called Anti-cancer agents or cytotoxic agents. 

These are especially indicated for malignant diseases in children and adults with malignant lymphomas, histiocytic lymphoma, non-Hodgkin’s lymphoma, chronic granulocytic leukaemia, mycosis fungoides, and many more.

 Before taking the medication, it is essential to know about the cyclophosphamide uses and side effects in the body.

The medicine is not recommended for those who have acute infections, urinary tract infections such as cystitis, acute urothelial toxicity, bone-marrow aplasia and many others. 

How to Use Cyclophosphamide 500mg? 

Cyclophosphamide 500mg is available in the powder form and it is made into solution for the injecting in the body. 

Cyclophosphamide is the white crystalline powder in the clear glass injection vials. 

The Cyclophosphamide medicine needs to be taken only from clinicians who are well experienced in cancer chemotherapy. 

Cyclophosphamide requires the doctor to administer it and regularly monitor biochemical and hematological parameters. 

Dosage is individualized based on the health condition. Order Cyclophosphamide 500mg from Sanford Pharmacy and get delivered at your doorstep.

Based on analyzing your health condition, doctors would be prescribing the dosage for cyclophosphamide tablet. 

Treatment Doses and duration depend on the therapeutic indication, the patient's general state of health, combination therapy, organ function and many more.

 Cyclophosphamide is available in various dosages, such as 

• 80 - 300 mg/m2 daily = single IV dose daily
• 300 - 600 mg/m2 = single IV dose weekly
• 600 - 1500 mg/m2 = Single IV dose or short infusion at 10-20 day intervals

Cyclophosphamide dosage will be provided with a combination of varied cytostatics. 

Dosage reduction or even extension is decided by the doctor. Activation of cyclophosphamide also involves hepatic metabolism. 

Hematopoiesis-stimulating agents are also used to reduce the risk of myelosuppressive complications or even help facilitate the delivery of dosing. 

Knowing how long does cyclophosphamide stay in your system is essential before taking the medication for treating the cancer.

 Intravenous administration is made with infusion. Intravenous or oral administrations are highly efficient. 

These are given directly in the tubing of fast-running IV infusions on supine. 

Duration and volume are adjusted based on the fluid infused.   

Missed Dose:

Whether you have missed a dosage of Cyclophosphamide 500mg then it is essential to consult doctor for taking the medicine for getting full effect. You must not overdose or double dose for the missed medication dosage. 

Overdose:

Overdosage of Cyclophosphamide 500mg can cause serious consequences such as Myelosuppression, Urotoxicity, Cardiotoxicity, Veno-Occlusive Hepatic Disease, Stomatitis and much other dose-dependent toxicity. 

Patients who have received the overdosing of medicine need to be closely monitored in case of any development of toxicities or haematotoxicity.

 Overdosage can be managed using supportive measures like state-of-the-art treatment for concurrent infection and myelosuppression.

Precautions and Warnings:

Before taking the Cyclophosphamide 500mg, it is important to know and follow the precautions. Following the precautions would be significantly be helping to reduce the side effects in body. 

• Patients With Hepatic Impairment:

Patients suffering from the hepatic impairment must avoid taking the cyclophosphamide. These could be altering effectiveness of cyclophosphamide in the body. 

• Pregnancy:

Cyclophosphamide 500mg is highly contraindicated in pregnancy, and it also crosses the placental barrier. 

Cyclophosphamide Treatments also involve a genotoxic effect that causes foetal damage administered to pregnant women. 

Women and men need to wait for about 12 months to attempt to conceive or father a child after stopping taking the Cyclophosphamide. 

Taking the Cyclophosphamide during pregnancy could be causing Malformations in children. 

Exposure to cyclophosphamide in utero could also be causing foetal growth retardation, miscarriage, and even manifesting newborn.

• Breastfeeding:

Taking Cyclphosphamide medicine during breastfeeding could be affecting the infant through breast milk. Child could have more symptoms such as Neutropenia, thrombocytopenia, diarrhoea and low hemoglobin. Women should avoid breastfeed during Cyclophosphamide treatment.

• Fertility:

Cyclophosphamide would also be interfering with the Spermatogenesis and Oogenesis. These can be causing sterility for both men and women. 

Cyclophosphamide-induced sterility is quite irreversible for the patients. 

The development of sterility could be based on cyclophosphamide dosage, gonadal function, and therapy duration.

• Elderly:

Monitoring for toxicities is essential for elderly patients. Doctors would suggest dosage adjustments.

These also reflect a higher frequency of decreased hepatic, cardiac, and organ function. Cyclophosphamide is highly contraindicated with patients having 

• Bone-Marrow Aplasia
• Acute Infections
• Hypersensitivity 
• Acute Urothelial Toxicity 
• Urinary Tract Infection
• Urinary Outflow Obstruction

Cyclophosphamide must not be used on patients with non-malignant disease unless it is used in immunosuppression or life-threatening situations. 

Cyclophosphamide is highly helpful for treating the cancer cells. You can take the Cyclophosphamide 500mg with food if you are experiencing the stomach irritation.

Side Effects of Cyclophosphamide 500mg:

Before taking the Cyclophosphamide 500mg, it is essential to know about the Side effects. Below are some of the common cyclophosphamide side effects you could be facing while taking the medication. You can buy Cyclophosphamide 500mg from Online Sanford Pharmacy.

• Hair loss
• Decreased white blood cell count (neutrophils),
• Myelosuppression
• Cystitis
• Infection
• Decreased white blood cell count or lymphocytes
• Microhematuria

When you are facing these worsening side effects in your body, then you need to consult a doctor immediately. 

Storage:

Store the Cyclophosphamide 500mg in a cool and dry place

Keep the medicine away from children and pet

Dispose of unused or expired Cyclophosphamide medicine 

Interactions:

Planned co-administration or sequential administration of Cyclophosphamide 500mg is essential for getting full effect. Severity of toxic effects varies with numerous aspects. 

Cyclophosphamide also interacts with other medicines so consult doctor before taking the medicine Patients receiving combinations of medicines are closely monitored for signs of toxicity. Interactions with Cyclophosphamide could be causing side effects.  

• Aprepitant
• Bupropion
• Busulfan
• Prasugrel
• Fluconazole
• Chloramphenicol
• Itraconazole
• Sulfonamides
• Thiotepa
• Ciprofloxacin
• Chloral hydrate
• Allopurinol
• Protease inhibitors
• Glyceraldehyde
• Disulfiram
• Cimetidine
• Bupropion
• Cyclosporine
• Coumarins
• Depolarizing muscle relaxants
• Digoxin, β –acetyldigoxin

Consult doctor if you are already taking these medicines for various purposes. Check out the cyclophosphamide cost in online before making a purchase for saving your money. At Sanford Pharmacy, we recognize the significance of this medication and are dedicated to making it accessible to those in need.

Frequently Asked Questions about Cyclophosphamide 500mg (FAQs):

Can Cyclophosphamide 500mg Cause Infertility?

Yes, taking the Cyclophosphamide 500mg could cause infertility in men and women. These could be interfering with the normal menstrual cycle of women. The medicine could also stop sperm production in men. Talk to your doctor about the cryopreservation of sperm or eggs prior to treatment.

Should I Avoid Sun Exposure During Cyclophosphamide Treatment?

There is no evidence that sun exposure affects the body while taking Cyclophosphamide.

Is The Cyclophosphamide Used For Non-Cancer Conditions?

Cyclophosphamide is also used for treating the nephrotic syndrome in children. These are also used in children having intolerable side effects with other medications.

Is Cyclophosphamide 500mg A Chemotherapy Medicine?

Cyclophosphamide is normally the chemotherapy medicine which comes under the alkylating agents. The Cyclophosphamide 500mg works with killing the cancer cells. 

Will The Cyclophosphamide Cause Weight Loss?

Yes, cyclophosphamide could cause weight loss due to reduced appetite. Reduction in weight is due to underlying cancer.